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Virologica Sinica, 02 (1) : 24, 1987
MECHANISM OF INTERFERON ACTION——Ⅹ. Conditioned antiviral effect of pppA2′p5′A2′p5′A
Institute of Genetics
Academia Sinica
BeijingDept. of Microbiol.
Nanjing Medical College
NanjingShanghai Institute of Biochemistry
Academia Sinica
This study showed that the treatment of pppA2 P5 A2 P5 A(2 -5 P_3A_3) on Lpa cells of mice in vitro makcs them possible to resist the challenge of Newcastle disease virus and vesicular stomatitis virus, giving further evidence for the general antiviral effect of 2′-5′P_3A_3.Conditions for getting positive antiviral effect of 2′-5′ P_3 A_3 were the quantity of challenging virus and the time for observing the results. 2′-5′P_3A_3 showed antiviral effect even if 2′-5′P_3A_3 was administrated 3-6 hr prior to vi...
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  Published online: 5 Mar 1987
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