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Virologica Sinica, 02 (3) : 34, 1987
Review
HUMAN CYTOMECALOVIRUS LATENCY IN HUMAN EMBRYONIC FORESKIN CELLS IN VITRO
Department of Virology
Wuhan University
Wuhan
 Correspondence:
(456.94KB)  
Abstract
Human cytomegalovirus(HCMV)latency model in human embryonic foreskin cells(HEF)was established with 500ng/ml of Tunicamycin(TM) which is a glucosamine-containing antibiotic that specifically inhibits glycosylation of proteins. Toxic effects in confluent monolayer cultures occurred when more than 500ng/ml of TM was used. The different concentrations of TM reduced the yield of HCMV to varying degrees, however, HCMV was not totally inhibited. At 5 days postinfection HCMV was not detectable at a TM concentratio...
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  Published online: 5 Sep 1987
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