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Virologica Sinica, 02 (3) : 50, 1987
Review
POTENTIATION OF INTERFERON S ANTIVIRAL ACTIVITY BY COMBINED PREPARATIONS OF HUMAN ALPHA AND GAMMA INTERFERONS
Department of Microbiology
Nanjing College of Chinese Traditional Medicine: NanjingSun Yatsen University of Medical Sciences
Guanzhou
 Correspondence:
(282.05KB)  
Abstract
Potentiation of interferon s antiviral activity was determined by replication inhibition of vesicular stomatitis virus in human lung cancer calls(A549). Combined preparations of human IFN-α and IFN-γ interacted with cells synergistically to cause a much grearer level of protection than that expected on the basis of their additive or multiplicative effect. The potentiation was not the artifact of an accelerated development of IFN-γ-induced antiviral resistance in the presence of IFN-α. The rest components in...
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  Published online: 5 Sep 1987
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