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Virologica Sinica, 03 (1) : 27, 1988
Study of Biological Properties of Cell Lines Transformed by Herpes Simplex Virus
Department of Microbiology
Shandong Medical University
The biological properties of three cell lines transformed by HSV-2 were investigated. The results indicate that the transformed cell lines possess the following characteristies:(1) chromosomal abnormalities; (2) reduce of requirement for serum factor; (3) rapid growth; (4) colony formation in soft agar; (5) increase of agglutination by Con Aand(6) induction of malignant tumor in nude mice These strongly suggest that the transformed cells are neoplastic.
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  Published online: 5 Mar 1988
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