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Virologica Sinica, 03 (4) : 343, 1988
Inhibitory Effect of IFN-α and IFN-γ on the Persistent Infection of HSV-Ⅱ
Faculty of Microbiology of Nanjing Medical College
K_(562) cells were challenged with HSV-Ⅱ virus and then cultured for successive reproduetion. In the supernatants of the culture no virus was tested in the 2nd and 3nd generations, but in the 4th generation the virus titer was found to be around 10~3TCD_(50). The culture wes carried on smoothly for 12 generations in 74 days. We observed not only the whole course of the persistent in fecton of HSV-Ⅱ on K _(562) cells, but also the influence of IFN-α,IFN-y and crude interleukin 2 on the persistetn infection. ...
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  Published online: 5 Dec 1988
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