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Virologica Sinica, 03 (4) : 389, 1988
Production and Some Properties of Porcine Spleen Interferon
Wuhan Institute of Virology
Academia Sinica
Porcine spleen cells induced with Newcastle disease virus F strain could produce an antiviral substance. The substance was sensitive to trypsin and did not penetrate the dialyser. These indicated that it was characteristic of an Interferon. The antiviral activity of crude porcine spleen cell interferon(PSIFN)was 1.3×10~5u/ml on porket kidney cells. PSIFN production was significantly enhanced by pretreating cells with porcine IFN. The crude PSIFN was less stable to low pH treatment, to 56℃ and to 0.1% SDS. I...
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  Published online: 5 Dec 1988
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