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Virologica Sinica, 04 (2) : 135, 1989
Analysis of Poliovirus Antigenic Epitopes by Immunofluorescence Activated McAbs
Institute of Medical Biology
Chinese Academy of Medical Sciences
12 McAbs to several strains of poliovirus Type 2 and 3 were selected by IF and NT, 9 McAbs had both neutralizing and immunofluorescence activity,3 McAbs were uniquely with IF staining activity. All the 12 McAbs with immunofluorescence activity reacted with poliovirus Type 2 and 3(F-McAbs) and were found similar to neutranizing McAbs (N-McAbs) recognizing different spesific antigenic epitopes on infected cells. According to topological relationships of antigenic epitopes, it was possible to characterize the ...
  Published online: 5 Jun 1989
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