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Virologica Sinica, 04 (2) : 159, 1989
Researches on Pre-S Proteins of Hepatitis B Virus Ⅵ. Binding of Pre-S Proteins with Human Serum Albumin
Division of Clinical Immunology
Tongji Hospital
Tongji Medical University
40 serum samples were used to study the relation of Pre-S_1 and pre-S_2 proteins to polymerized human serum albumin receptor (PHSAR). Our results suggested that pre-S_2 may be the main binding site for PHSA, but pre-S_1 may also possess the activity to bind PHSA. Pre-S_1, pre-S_2 and PHSAR may be blocked in vitro by pretreatment with PHSA and the negative correlation between the blocking rate and the dilution of PHSA was seen. We also showed that the complexes of HBV envelop protein-human serum albumin may ...
  Published online: 5 Jun 1989
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