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Virologica Sinica, 04 (3) : 266, 1989
Replication of HFRS Virus in Cultured Human Lymphoblastoid Cells with B Cell Characteristics
Lab of HFRS/Inf Dis Dept
Second Affiliated Hosp
Fourth Millitary Med College
The susceptibility of human B lymphoblastoid cells to HFRS virus infectionwas studied. The results showed that the cells were productively infected byHFRS virus. The persistently infected cells had no obvious cytopathic effects andwere indistinguishable morphologically from uninfected cells. It was difficult toidentify complete virions in infected lymphoblasts by electron microscopy con-trasted with strong immunofluorescence staining for intracellular HFRS virusantigens observed in the majority of these cel...
  Published online: 5 Sep 1989
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