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Virologica Sinica, 04 (4) : 375, 1989
Review
Isolation of Enterovirus Type 71 from the Vesicle Fluid of an Adult Patient with Hand-footmouth Disease in China
Virus Research Institute
Hubei Medical University
Wuhan
 Correspondence:
(1582.78KB)  
Abstract
Isolation and characterization of a H isolate of enterovirus type 71 (E71) from the vesicle fluid of hand-foot-mouth disease have been reported in present study.The H isolate can grow at primary human embryo lung cells, MA104 cells, and BSC cells and results in a typical enterovirus cytopathic effect. 1-day-old mice inoculated ip with H isolate showed limb paralysis and died at 6th day postinfection. Numerous mature virus particles with a diameter of 25 nm in crystal arrays in the cytoplasm have been visual...
  Published online: 5 Dec 1989
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