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Virologica Sinica, 05 (2) : 162, 1990
The Preparation of Monoclonal Anti-idiotypic Antibodies Against Mouse Monoclonal Anti-HBs and Their Immunogenicity Ⅱ.The Study on Immunogenicity of Ab_2-1
Institute of Microbiology and Epidemiology Academy of Military Medical Sciences
Beijing 100071
The Ab_2-1 was used to immunize four BALB/c mice and two rabbits. Each mouse recievcd inoculation of 100μg of Ab_2-1 for four times intraperitoneally. Each rabbit was injected with 1 mg of Ab_2-1 for four times subctaneously. All the mice and rabbits immunized with Ab_2-1 produced anti-HBs antibodies, specificity of which also was confirmed by two types of competitive inhibition test(SPRIA). The titers of mouse anti-HBs were from 2~(-6) to 2~(-9) the anti-HBs titers of rabbit sera varied from 2~(-10) to 2~(...
  Published online: 5 Jun 1990
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