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Virologica Sinica, 05 (4) : 367, 1990
Studies on Antiviral Activity of the Extract of Monordica Charantca and its Active Principle
Institute of Virology
Chinese Academy of Preventive Medicine
Beijing 100052
The extract of Monordica charantia (E. M. c.) was found to have a significant protective effect on Japanese B encephlitis virus infection in vivo. When mice were administered intraperitoneally with a dose of 0.4 mg E. M. c. at 18 hr, 12 hr, 4 hr before subcutaneous challenge with the virus respectively, the protective rate of treated group is 66%. E.M.c. was demonstrated as an interferon inducer. Type I IFN was found in rabbit serum and its level peaked at 2hr after intravenus injection of E. M.c. E.M.c. en...
  Published online: 5 Dec 1990
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