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Virologica Sinica, 06 (2) : 143, 1991
Purification and Characterization of HFRS Virus Glycoproteins
Jiangxi Institute of Medical Sciences
Nanchang 330006
Two HFRS virus glycoproteins with molecular weight of 78K and 57K were purified by immunoaffinity chromatography with preparative SDS-PAGE from virus-infected cells Purified 78K and 57K glycoproteins all showed only one band on SDS-PAGE and have antigenieity and immunogenicity, The results of hemagglutination test indicate that 57K glyeoprotein has hemagglutation activity. Neutralizing test with antisera confirm both 78K and 57K glyeoproteins have neutralizing antigenic determinants. These results suggest t...
  Published online: 5 Jun 1991
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