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Virologica Sinica, 06 (3) : 183, 1991
Inhibitory Effect of HSV Infection in Vitro on IgG and Effect of TNF and r-IFN on It
Dept.of Microbiology
Nanjing Medical College
Nanjing 210005
We successfully established a system in vitro that HSV-Ⅰ infected human tonsillar lymphocytes. Tonsillar lymphocytes prestimulated with PWM(10μg/ml) were infected by living HSV-Ⅰ, so as to their proliferation and IgG synthesis were abated significantly(P<0.005).In the supernatants, the infective titers ofHSV-Ⅰ were about 10~(3?2)—10~(5?7) TCID_(50)/ml,number of viral antigen positive cells about 3%—8%.We found that some lymphokine and monokine can dampen the inhibition of infection of infectious HSV-Ⅰ Th...
  Published online: 5 Sep 1991
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