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Virologica Sinica, 06 (3) : 207, 1991
Review
Specific HSV-I Antibody Production in Vitro by Human Peripheral Lymphocytes andEnhancement by IFNγ
Department of Microbiology
Nanjing Medical College
Nanjing 210029
 Correspondence:
(205.71KB)  
Abstract
Human peripheral blood lymphocytes from normal adult donors were stimulated in vitro by UV-inactived Herpes simplex virus type Ⅰ(HSV-Ⅰ) as an antingen, incubated in 37℃ for 12 days. Specific anti-HSV-Ⅰ antibody was measured by ELISA Anti-HSV antibody of IgG type was produced in vitro in all 11 individuals (26.6±23ng/ml) whose sera were sero-positive to HSV-Ⅰ. Newborn lymphocyte cultures failed to induce anti-HSV-Ⅰantibody of IgG or IgM type after stimulation. The anti-HSV-I antibody response of lympb0cytes ...
  Published online: 5 Sep 1991
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