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Virologica Sinica, 06 (3) : 271, 1991
Review
Discovery and Study of a Neutralizing Antigen Broad HFRS Virus Strain Gou3
National Institute for the Control of Pharmaceutical and Biological Products
Beijing
100050Anhui Institute of Medical Science
Hefei Zhejing Health and Anti-epidemlc Station
Hangzhou
 Correspondence:
(65.57KB)  
Abstract
Antigenicity of a HFRS virus strain, Gou_3, isolated from Rattus norvegicus, was studied by plaque reduction neutralization test. Anti-Gou_3 rabbit serum was used for neutralization with ten Type 1 HFRS viruses and_4 Type 2 viruses. The results revealed that anti-Gou_3 serum reacted to almost the same of neutralizing titer with most of the virus strains in both types, indicating that Gou_3 is a neutralizing antigen broad virus strain. This is the first discovery and it is of significance in selection of see...
  Published online: 5 Sep 1991
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