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Virologica Sinica, 06 (4) : 281, 1991
Review
Identification of the Morphological Transforming Regions of Human Cytomegalovirus
Department of Microbiology Georgetown University Medical Center Washington
Jinan University Medical College
Department of Microbiology Georgetown University Medical Center Washington
D.C.20007 USA
 Correspondence:
(268.90KB)  
Abstract
DNA of human cytomegalovirus (HCMV) contains three transforming fragments, which have been mapped in the long unique region of the viral genome(see Fig.1). A minimal region of 558 base pairs(bp) (pCM4127) was localized in the XbaI-Hindlll fragment of HCMV strain AD169 (mapunit 0.123—0.140)and designated morphological transforming region Ⅰ (mtrⅠ). MtrⅠwas reported to cause one-step focal transformation of primary Wistar
  Published online: 5 Dec 1991
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