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Virologica Sinica, 07 (1) : 43, 1992
Review
The Function of Poliovirus 2A Proteinase in the Polio-Vaccinia Recombinant Virus
Institute of Medical Biology
Chinese Academy of Medical Sciences
Kunming 650107
 Correspondence:
(140.51KB)  
Abstract
For studying the function of Poliovirus 2A proteinaes in Polio-Vaccinarecombinant virus, We constructed the various chimeric virus of Polio-Vac-cinia, and obtained 4 Polio--Vaccinia recombinant viruses which contain var-ious fragments of Polio virus I type mahoney strain gene. These fragmentswere inserted into the TK region of vaccinia gene. The antigen of Polioviruswas expressed in these 4 recombinant viruses, the antibody against Poliovirusl type was induced in the rabbit infected by these chimeric viruse...
  Published online: 5 Mar 1992
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