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Virologica Sinica, 07 (1) : 48, 1992
Review
Analysis of peptides of HBsAg and the Epitopes of "a" Determinant by Monoclonal Antihody
National Institute for the Control of Pharmaceutical and Biological Products
Beijing 100050
 Correspondence:
(166.10KB)  
Abstract
Five selected McAbs were tested for their binding to HBsAg polypeptidecomposition by using Western Blot. McAb B_6, B_9 and B_(12) combined polypeptideP24 of HBsAg, while McAb A_1 and B_(13) combined both polypeptide p24 andP27 of HBsAg. Using the five McAbs, the epitope density of "a" determinantof HBsAg derived from different sources was also studied with the second an-tibody method. The result showed that there was similar density of epitopesagainst five McAbs on plasma-derived HBsAg (PD HBsAg), CHO cell-...
  Published online: 5 Mar 1992
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