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Virologica Sinica, 07 (3) : 259, 1992
Detection of Human Papillomavirus Type 16 DNA in Head and Neck Tumors
Virus Research Institute
Hubei Medical College
Wuhan 430071
In order to probe the relatignship between human papillonavirus type 16 and head-neck tumors, using fresh tissue and paraffin-embeded tissue sections preparing DNA to detect HPV16 DNA in head and neck tumor, by PCR and hybridization technique. The results showed that HPV16 DNA sequences were positively amplified in one laryngeal papilloma (11.1%), in 3 inverted papillomas of the nose (42.9%). in 4 laryngeal squamous cell earcinomas(20%).in 3 oral eaneers(27.3%). LSCC of glottie origin showed higher PHV16 DN...
  Published online: 5 Sep 1992
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