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Virologica Sinica, 07 (4) : 389, 1992
Review
Expression of Hepatitis B Virus Surface Antigen Using a Baculovirus Vector with the Polyhedrin Gene
Institute of Entomology
Zhongshan University and National Laboratory of Biological Control
Guangzhou 510275
Virology Research Unit
Fudan University
Shanghai 200433
 Correspondence:
(215.82KB)  
Abstract
Using a polyhedrin-positive transfer plasmid and a nonoccluded (OCC-) parental recombinant, an occluded (OCC~+)recombinant baculovirusdesignated TnNPV-HBs85-OCC~+ was successfully constructed which contained the gene coding for the hepatitis B virus surface antigen under the dual control of the synthetic and XIV promoters, Infection of Tvichoplusia ni larvae with TnNPVHBs85-OCC~+ can be introduced as a contaminant of the diet rather than the conventional baculovirus OCC~- expression vector in which the reco...
  Published online: 5 Dec 1992
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