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Virologica Sinica, 08 (1) : 45, 1993
The Cloning and Characterization of the Genome of Human Papilloma Virus Type 16 in China
Institute of Oncology
Beijing 100021
The cloning and characterization of a whole genome of human Papillomavirus type 16 (7.9kb) and a 5.4kb subgenomic fragment are presented here for the first time in China. Both of them were cloned in HB101 after insertion in plasmid pAt153, using it s unique BamH1 site. The full-length genome and subgenomic fragment are designated HPV16Z and HPV16F, respectively. After analysis of 16 endonucleases, none of new endonuclease site were found in HPV16Z comparing with standard strain. A new BamH1 site was observe...
  Published online: 5 Mar 1993
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