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Virologica Sinica, 08 (3) : 290-292, 1993
An Experimental Animal Model Study on Infection and Pathogensis of HCMV-AD_(169) Strain
Institute of Virology Hubei Medical College
This paper is a study on the result of animal model with HCMV. Rabbits were inoculated with HCMV-AD_(169) strain. The duration of viremic stage of rabbits infected with HCMV was studied by means of immunoflourescent assays and reisolation of the virus. Specific flourescence for HCMV anti- gen was first observed in both monocytes and lymphocytes in the blood on 13th day,and released the virus to the plasma. It was indicated that HCMV was disseminated to rabbits body, thus caused target or- gans infection.
  Published online: 5 Sep 1993
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