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Virologica Sinica, 08 (4) : 332-337, 1993
Review
In Vitro and in Vivo Heptatitis B Virus (HBV) Inhibiting Bone Marrow Mononuclear Cells Producing Interleukin-1 and Interleukin-2
Dept of Infecious Diseases
Union Hospilal
Tongji University
Wuhan
430022
 Correspondence:
(164.63KB)  
Abstract
The levels of interleukin-1 and interleukin-2 production in 16 healthy blood donors bone mar row mononuclear cells infected by HBV in vitro and on 16 cases with chronic hepatitis B were simulta neously assayed. The evidence of virus growth is based on the detecion of HBcAg in bone marrow mononuclear cells by immunoperoxidase assay. It was found that HBcAg is positive in 50% (in vitro) and 43. 7%(in vivo) respectively (P<0.05). The levels of interleukin-1 and interleukin-2 produetion are markedly decreas...
  Published online: 5 Dec 1993
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