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Virologica Sinica, 08 (4) : 338-340, 1993
Review
The TK Gene of Raccoon Pox Virus is not Sensitive to 5-BUdR
1~Wuhan Institute of Biological Products
Wuhan
430060
~2Centers For Disease Control
Allanta
U. S. A
 Correspondence:
(97.78KB)  
Abstract
In this assay,we studied the possibility of raccoon pox virus (RCN) TK gene as a viral selection marker on Rat-2 cells. Southern blot showes that RCN has TK gene sequence though it hybridizes week ly with vaccinia virus TK gene. But RCN is resistant to 5-BUdR even after it was plaque purified in HAT media.
Key Words: Raccon poxvirus;  TK gene;  5-BUdR
  Published online: 5 Dec 1993
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