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Virologica Sinica, 09 (1) : 81, 1994
Observation of Pathological and Viral Antigen of Epidemic-Hemorrhagic Fever Virus Infection in Suckling Mice
Hubei Medical University
Epidemic hemorrhagic fever virus origined from patients with epidemic hemorrhagic fever was inoculated into suckling mice,The results showed that the suckling mice died regularly,The viral antigenand pathological damage appeared in the brain,lung,liver and kidney,The characterization of patho-logical changes were congestion, hemorrhage and degeneration of blood vessels.The viral perticles canbe found in hippocampus region,The viral antigen can be detected in cytoplasm.The resultS suggestthat suckling mice were susceptible for human original epidemic hemorrhagic fever virus.
  Published online: 5 Mar 1994
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