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Virologica Sinica, 09 (4) : 291, 1994
Review
Polymerase chain reaction for detection of different types of tiuman papillomavirus ill tile cervix
Dep. of Microbiology, Nanjing Medical University
 Correspondence:
(152.98KB)  
Abstract
Polymerase Chain Reactiun(PCR)was used to detect HPV 6,11,16,18 type specific DNA se-quences in 2l2 clinical cervical samples.The pusitivity uf HPV-DNA was 62.5%(25/40)in patientswith cervical cancer(squamous cell)and 57%(81/142)in chronic cervicitis,markedly higher than20%(6/30)in hedlthy control(P<0.001).HPV-16 was predominantly related to cervical cancerwhereas HPV-6,16,18 frequently inchronic cervicitis.This study also indicated that multiple infection of different HPV types is common(3 l.3%)and the rate of HPV positivity showed no associationwith age-dependence(P>0.05).
  Published online: 5 Dec 1994
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