Hello guest, Register  |  Sign In
Virologica Sinica, 11 (4) : 348, 1996
Review
Pharm acodynam ics Studies of Alternanthera philoxeroides Griseb in Oral for EHFV Infection in Suckling Mice
Virus Research Institute,Hubei Medical University,Wuhan 430071Hubei Traditional Medical College.Wuhan 430060
 Correspondence:
(107.60KB)  
Abstract
Antiviral effect of Alternanthera philoxeroides Griseb(APG)was studied in oral for epi-demic hemorrhagic fever virus(EHFV)infection in suckling mice.The APG dosages of A,BandC groups were 5mg/(g·d),7.5mg/(g·d)and 10mg/(g·d),respectively. The results showedthat the survival rate of A,B and C group were 80.0%,72.2% and 40.0%,the means time day(MTD)were 56.5±0.9, 53.5±1.1 and 41.5±2.7 day,respectively.The survival rate and MTD were 0.0% and 26.3±0.8 day in untreated viral control group.The antiviral effect of theAPG was similar with the ribavirin.This indicated that the APG was effective in treatment of epidemic hemorrhagic fever.
  Published online: 5 Dec 1996
Home |  Resources |  About Us |  Support |  Contact Us |  Privacy |  Powered by CanSpeed | 
Copyright © 2015 Virologica Sinica. All rights reserved