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Virologica Sinica, 12 (3) : 235, 1997
Review
Molecular cloning and sequencing of ribozyme region of HDV from a serious hepatitis patient
 Correspondence:
(110.22KB)  
Abstract
The cDNA (651nt - 941nt) fragment of an isolate of hepatitis delta virus with 289 bp was determined by cloning and Sequencing, from a HBsAg carrier positive both for anti - HDAg and HDV RNA from China, Sichuan Province, using reverse transcription polymerase chain reaction.It contains the region of HDV ribozyme and its self - cleavage site. Comparing this Sichuan isolate with other known HDV isolates from Henan, US - 1, Japan, Peru and Taiwan, the result showed that the homology of nucbotides is 97. 2 %, 93 %, 94 %, 79 %, 96 %, respectively.
  Published online: 5 Sep 1997
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