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Virologica Sinica, 12 (4) : 309-312, 1997
Pathogenicity of Herpes Sim plex Virus on Mice
Guangzhou General Hospital of Chinese PLA Guangzhou 510010
The pathogenicity of herpes simplex virus(HSV)in mice宙as observed.The mice appears
syndrome and sign afterinoculation 4 days HSV could beisolatedinthe blood on 2hours po$tin—
fection.The isolation rate of HSV and levd of viremia were increased on 48 hours postirfection.
distributions of HgV wel'e differem in virious tissues.The HSV titers in brain and seusory
ganglion reached the p目_k on 72 hours postinfection,but in heart and liver on 5 days.Above re·
sults showed that the patho geniclty model of HSV can be used to search anti—HSV agents.
  Published online: 5 Dec 1997
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