Hello guest, Register  |  Sign In
Virologica Sinica, 13 (1) : 45, 1998
Review
The Inhibitory Effects of Enduracidin on Hepatitis B Virus in vitro
School of Pharmacy,Shanghai Medical Universlty,Shanghai 200032
 Correspondence:
(141.56KB)  
Abstract
Enduracidin was studied for its ability to inhibit Hepatitis B Virus DNA, HBsAg and HBeAg secreted by a HBV transfected cell line (HepG 2.2.2.15). The result showed that IC 50 (the drug concentration that inhibits HBsAg or HBeAg secretion by 50%)was 27μg/mL and 34μg/mL respectively, theraputic index (TI) was 5.9 and 4.6. Enduracidin at the concentration of 50μg/mL inhibited 56.8% of the production of free HBV DNA in the Cells.
  Published online: 5 Mar 1998
Home |  Resources |  About Us |  Support |  Contact Us |  Privacy |  Powered by CanSpeed | 
Copyright © 2015 Virologica Sinica. All rights reserved