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Virologica Sinica, 15 (1) : 34, 2000
Identification and primary application of fusion-inhibiting active monoclonal antibody of respira- tory syncytial virus
Anhui Medical University
Monoclonal antibody of F 3 hybridoma cell strain against RSV specific antigen was prepared by hybridoma and tested by indirect immunofluorescence and ELISA. It has neutralizing and fusion inhibiting activity. The neutralizing titres and fusion inhibiting titres of ascites of mice are 1∶128 and 1∶64 respectively. Clinical diagnosis by comparing McAb of F 3 strain with fixed McAb of commerical kit show that the positive according rate are 96.9% and negative according rate are 100%. F 3 hybridoma cell strain probably produces a monoclonal antibody against fusion protein of RSV.
  Published online: 5 Mar 2000
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