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Virologica Sinica, 17 (2) : 97-101, 2002
Contents
Cloning and Analyzing a New PEBP Like Protein Gene in Human Fibroblast Cell Infected by HSV I
Department of Viral and Immunology,Institute of medical Bio1~gy,CAMS and PUMC,Kunmlng 650118,China
 Correspondence:
(200.72KB)  
Abstract
In our study on the gene response to virus infection,a colony of 705bp—HSP一714 was se—
lected from the cell specific cDNA library induced by HSVI infection.The gene sequence analysis re·
vealed that it was a new complete gene sequence(Gene Bank Accession number~AF372624)with a
complete ORF encoding 126 amino acids.The biological informatics aiualysis demonstrated that this
pmtein contained a phosphatidylethanolamine—binding protein(PEBP)like domain,which had a high
homology to the CEN—like family of plant and mam malian ete.genome.Furthermore,the evolution tree
demonstrates that this gene shows more homologous to CEN—like family Of plant Therefore.it can be
predicted that this gene might be a new member of human PEBP—like family with special significance
  Published online: 5 Apr 2002
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