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Virologica Sinica, 18 (6) : 566-570, 2003
Research Article
The Study on the Infection of Rabbits with Bovine Foamy Virus 3026’
College of Life Sciences,Nankai University,Tianjin 300071, P.R.China
Abstract:Rabbits were injected with a single intravenation of Bovine foamy virus 3026(BFV3026)·
infected cells in the ear and monitored for sera-conversion serologically up t0 l year.Results of the
serological an d virus-rescue assays indicated that all animals were persistently infected with BFV3026
an d showed sustained BFV3O26.spec ific humoral immune response.BFv3026 Was rescued by
co-cultivation with fetal bovine lung(FBL)cells from the spleen,kidney,lung,liver and peripheral
blood leukocytes of the infected an imals.Virus sequence in poZ was、recovered an d amplified from the
tissues where the virus Was rescued from,such as from the heart,brain,bone marrow,mesentery an d the
pan creas.In addition.BFv transcripts could be detected in PBL by RT.PCR. S animal model might
be usefulfor studyingtheinteractionbe tweenBFv an dBIV
  Published online: 25 Dec 2003
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