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Virologica Sinica, 19 (6) : 620-623, 2004
Research Article
Sequencing and Phelogenetic Analysis of Hypervariable Region of Infectious Bursal Disease Virus vp2 Gene
Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
Hypervariable region of vp2 gene of six different IBDV (Infectious bursal disease virus) isolates, which were isolated from Jiangsu province, was amplified by RT-PCR and sequenced. Furthermore, sequences of six IBDV isolates were analyzed by ClustalX and Phylip3.5. It was suggested that three isolates (Y3, P2G, P8G) were closely related to vvIBDV (very virulent IBDV) strains isolated from China and Europe. Other isolates (SZ, Y5, W04) were very close with Japanese vvIBDV strains. This study laid on foundation for the research of molecular epidemiology and the development of IBDV vaccines.
  Published online: 20 Dec 2004
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