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Virologica Sinica, 23 (5) : 305-314, 2008
Contents
Current Status of Natural Products from Plants as Anti-Herpes Simplex Virus 1 Agents
Biomedicine Research & Development Center, Jinan University, Guangzhou 510630, China
 Correspondence:
(242.08KB)  
Abstract
Abstract: Nucleoside analogues have been the mainstay of clinical treatment of herpes simplex virus 1 (HSV-1) infections since their development. However, the emergence of drug resistant strains has underlined the urgency of the discovery of novel anti-HSV-1 drugs. Natural products, which provided many novel drug leads, are known to be an important source of anti-HSV-1 agents. Herein, we present an overview of natural products with anti-HSV-1 activities isolated from a variety of plants reported in recent years. Several different compounds, mainly belonging to the three groups of polysaccharides, polyphenols and terpenes, showed antiviral effects against HSV-1, indicating their potential to be promising anti-HSV-1 agents
  Published online: 5 Oct 2008
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