A Virulent PEDV Strain FJzz1 with Genomic Mutations and Deletions at the High Passage Level Was Attenuated in Piglets via Serial Passage In Vitro

• Pengfei Chen ^1,4 , 
• Xiongwei Zhao ¹ , 
• Shuting Zhou ² , 
• Tianxing Zhou ^1,3 , 
• Xiangmei Tan ¹ , 
• Xia Wu ¹ , 
• Wu Tong ¹ , 
• Fei Gao ¹ , 
• Lingxue Yu ¹ , 
• Yifeng Jiang ¹ , 
• Hai Yu ¹ , 
• Zhibiao Yang ² , 
• Guangzhi Tong ^{1,4 ,,} , 
• Yanjun Zhou ^{1,4 ,,}

cstr: 32224.14.s12250-021-00368-w

• 1.

  Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China

• 2.

  Shanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai JiaoTong University, Shanghai, 200240, China

• 3.

  College of Biological Science and Technology, Beijing Forestry University, Beijing, 100083, China

• 4.

  Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, 225009, China

• Corresponding author: Guangzhi Tong, gztong@shvri.ac.cn, ORCID: http://orcid.org/0000-0001-7048-0837
  Yanjun Zhou, yjzhou@shvri.ac.cn, ORCID: http://orcid.org/0000-0002-2524-0831