Virome diversity of ticks feeding on domestic mammals in China

Zijun Yang; Hao Wang; Shixing Yang; Xiaochun Wang; Quan Shen; Likai Ji; Jian Zeng; Wen Zhang; Haiyan Gong; Tongling Shan

doi:10.1016/j.virs.2023.02.001

April 2023

Citation: Zijun Yang, Hao Wang, Shixing Yang, Xiaochun Wang, Quan Shen, Likai Ji, Jian Zeng, Wen Zhang, Haiyan Gong, Tongling Shan. Virome diversity of ticks feeding on domestic mammals in China .VIROLOGICA SINICA, 2023, 38(2) : 208-221. http://dx.doi.org/10.1016/j.virs.2023.02.001

Virome diversity of ticks feeding on domestic mammals in China

Zijun Yang ^a,b,d ,
Hao Wang ^c ,
Shixing Yang ^b ,
Xiaochun Wang ^b ,
Quan Shen ^b ,
Likai Ji ^b ,
Jian Zeng ^b ,
Wen Zhang ^{b
,,} ,
Haiyan Gong ^{a
,,} ,
Tongling Shan ^{a
,,}

a. Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China;
b. Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, 212013, China;
c. Department of Clinical Laboratory, Huai'an Hospital, Xuzhou Medical University, Huai'an, 223002, China;
d. Center of Clinical Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China

Corresponding author: Wen Zhang, z0216wen@yahoo.com
Haiyan Gong, gonghaiyan@shvri.ac.cn
Tongling Shan, shantongling@shvri.ac.cn
Received Date: 26 April 2022
Accepted Date: 08 February 2023
Available online: 11 February 2023

Abstract

Ticks are considered the second most common pathogen vectors transmitting a broad range of vital human and veterinary viruses. From 2017 to 2018, 640 ticks were collected in eight different provinces in central and western China. Six species were detected, including H.longicornis, De.everestianus, Rh.microplus, Rh.turanicus, Rh.sanguineous, and Hy.asiaticum. Sixty-four viral metagenomic libraries were constructed on the MiSeq Illumina platform, resulting in 13.44 G (5.88×10⁷) of 250-bp-end reads, in which 2,437,941 are viral reads. We found 27 nearly complete genome sequences, including 16 genome sequences encoding entire protein-coding regions (lack of 3' or 5' end non-coding regions) and complete viral genomes, distributed in the arboviral family (Chuviridae, Rhabdoviridae, Nairoviridae, Phenuiviridae, Flaviviridae, Iflaviridae) as well as Parvoviridae and Polyomaviridae that cause disease in mammals and even humans. In addition, 13 virus sequences found in Chuviridae, Nairoviridae, Flaviviridae, Iflaviridae, Hepeviridae, Parvoviridae, and Polyomaviridae were identified as belonging to a new virus species in the identified viral genera. Besides, an epidemiological survey shows a high prevalence (9.38% and 15.63%) of two viruses (Ovine Copiparvovirus and Bovine parvovirus 2) in the tick cohort.
- Central and western China
- , Viral metagenomes
- , Tick-borne virus
- , Phylogenetic analysis
- , Domestic mammals
- , Tick virome

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Virome diversity of ticks feeding on domestic mammals in China

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Virome diversity of ticks feeding on domestic mammals in China

Corresponding author: Wen Zhang, z0216wen@yahoo.com

Corresponding author: Haiyan Gong, gonghaiyan@shvri.ac.cn

Corresponding author: Tongling Shan, shantongling@shvri.ac.cn

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