Serving the Society Since 1986
Advanced Search
Volume 39 Issue 6
December 2024
    Citation: Pengfei Hao, Zhaoxia Pang, Qiaoqiao Qu, Chunmei Cui, Yuhang Jiang, Jing Chen, Zihan Gao, Zhiqiang Xu, Letian Li, Ningyi Jin, Chang Li. A G3P[3] bat rotavirus can infect cultured human cholangiocytes and cause biliary atresia symptom in suckling mice .VIROLOGICA SINICA, 2024, 39(6) : 974-976.  http://dx.doi.org/10.1016/j.virs.2024.09.009
    shu

    A G3P[3] bat rotavirus can infect cultured human cholangiocytes and cause biliary atresia symptom in suckling mice

    cstr: 32224.14.j.virs.2024.09.009

    • a. State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China;

    • b. Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, 130122, China

    • Highlights
      1 Bat rotavirus strain MSLH14 (G3P[3]) can infect human cholangiocytes in vitro.
      2 MSLH14 can cause suckling mice biliary atresia symptom, indicating potential public health risks.
      3 MSLH14 have the potential for establishing a biliary atresia animal model.
    • 加载中

    • Electronic Supplementary Material

      10.1016j.virs.2024.09.009-ESM.docx

      1. Averbukh, L.D., Wu, G.Y., 2018. Evidence for viral induction of biliary atresia: a review. J Clin Transl Hepatol, 6, 410-419.

      2. He, B., Huang, X., Zhang, F., Tan, W., Matthijnssens, J., Qin, S., Xu, L., Zhao, Z., Yang, L., Wang, Q., Hu, T., Bao, X., Wu, J., Tu, C., 2017. Group A rotaviruses in Chinese bats: genetic composition, serology, and evidence for bat-to-human transmission and reassortment. J. Virol., 91, e02493-16.

      3. He, B., Yang, F., Yang, W., Zhang, Y., Feng, Y., Zhou, J., Xie, J., Feng, Y., Bao, X., Guo, H., Li, Y., Xia, L., Li, N., Matthijnssens, J., Zhang, H., Tu, C., 2013. Characterization of a novel G3P[3] rotavirus isolated from a lesser horseshoe bat: a distant relative of feline/canine rotaviruses. J. Virol., 87, 12357-12366.

      4. Jiang, J., Wang, J., Shen, Z., Lu, X., Chen, G., Huang, Y., Dong, R., Zheng, S., 2019. Serum MMP-7 in the diagnosis of biliary atresia. Pediatrics, 144, e20190902.

      5. Lertudomphonwanit, C., Mourya, R., Fei, L., Zhang, Y., Gutta, S., Yang, L., Bove, K.E., Shivakumar, P., Bezerra, J.A., 2017. Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia. Sci. Transl. Med., 9, eaan8462.

      6. Meng, F., Francis, H., Glaser, S., Han, Y., Demorrow, S., Stokes, A., Staloch, D., Venter, J., White, M., Ueno, Y., Reid, L.M., Alpini, G., 2012. Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration. Hepatology, 55, 209-221.

      7. Mohanty, S.K., Donnelly, B., Lobeck, I., Walther, A., Dupree, P., Coots, A., Meller, J., Mcneal, M., Sestak, K., Tiao, G., 2017. The SRL peptide of rhesus rotavirus VP4 protein governs cholangiocyte infection and the murine model of biliary atresia. Hepatology, 65, 1278-1292.

      8. Mohanty, S.K., Lobeck, I., Donnelly, B., Dupree, P., Walther, A., Mowery, S., Coots, A., Bondoc, A., Sheridan, R.M., Poling, H.M., Temple, H., Mcneal, M., Sestak, K., Bansal, R., Tiao, G., 2020. Rotavirus reassortant-induced murine model of liver fibrosis parallels human biliary atresia. Hepatology, 71, 1316-1330.

      9. Thomas, H., 2018. Biliary tract: MMP7-a diagnostic biomarker for biliary atresia. Nat. Rev. Gastroenterol. Hepatol., 15, 68.

      10. Wang, J., Xu, Y., Chen, Z., Liang, J., Lin, Z., Liang, H., Xu, Y., Wu, Q., Guo, X., Nie, J., Lu, B., Huang, B., Xian, H., Wang, X., Wu, Q., Zeng, J., Chai, C., Zhang, M., Lin, Y., Zhang, L., Zhao, S., Tong, Y., Zeng, L., Gu, X., Chen, Z.G., Yi, S., Zhang, T., Delfouneso, D., Zhang, Y., Nutt, S.L., Lew, A.M., Lu, L., Bai, F., Xia, H., Wen, Z., Zhang, Y., 2020. Liver immune profiling reveals pathogenesis and therapeutics for biliary atresia. Cell, 183, 1867-1883.e26.

      11. Xia, L.L., He, B., Hu, T.S., Zhang, W.D., Wang, Y.Y., Xu, L., Li, N., Qiu, W., Yu, J., Fan, Q.S., Zhang, F.Q., Tu, C.C., 2013. Isolation and characterization of rotavirus from bat. Bingdu Xuebao, 29, 632-637. (In Chinese).

      12. Yang, L., Zhou, Y., Xu, P.P., Mourya, R., Lei, H.Y., Cao, G.Q., Xiong, X.L., Xu, H., Duan, X.F., Wang, N., Fei, L., Chang, X.P., Zhang, X., Jiang, M., Bezerra, J.A., Tang, S.T., 2018. Diagnostic accuracy of serum matrix metalloproteinase-7 for biliary atresia. Hepatology, 68, 2069-2077.

    • 加载中

    Figures(1)

    PDF

    Article Metrics

    Article views(2334) PDF downloads(16) Cited by()

    Related
    Proportional views

      A G3P[3] bat rotavirus can infect cultured human cholangiocytes and cause biliary atresia symptom in suckling mice

        Corresponding author: Letian Li, letian823@163.com
        Corresponding author: Ningyi Jin, ningyik@126.com
        Corresponding author: Chang Li, lichang78@163.com
      • a. State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China;
      • b. Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, 130122, China
      • Received Date: 02 April 2024
      • Accepted Date: 23 September 2024

      Abstract: Highlights
      1 Bat rotavirus strain MSLH14 (G3P[3]) can infect human cholangiocytes in vitro.
      2 MSLH14 can cause suckling mice biliary atresia symptom, indicating potential public health risks.
      3 MSLH14 have the potential for establishing a biliary atresia animal model.

        HTML

      Figure (1)  Reference (12) Relative (20)

      目录

      This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE)

      鄂ICP备05001977号

         

      鄂公网安备 42010602003674号

      Copyright © 2019 Virologica Sinica. All rights reserved

      /

      DownLoad:  Full-Size Img  PowerPoint
      Return
      Return