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Volume 40 Issue 1
February 2025
    Citation: Ahmed H. Ghonaim, Sherin R. Rouby, Wedad M. Nageeb, Ashraf Ahmed Elgendy, Rong Xu, Changsheng Jiang, Noha H. Ghonaim, Qigai He, Wentao Li. Insights into recent advancements in human and animal rotavirus vaccines: Exploring new frontiers .VIROLOGICA SINICA, 2025, 40(1) : 1-14.  http://dx.doi.org/10.1016/j.virs.2024.12.001
    shu

    Insights into recent advancements in human and animal rotavirus vaccines: Exploring new frontiers

    cstr: 32224.14.j.virs.2024.12.001

    • a. National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China;

    • b. The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China;

    • c. Desert Research Center, Cairo 11435, Egypt;

    • d. Department of Veterinary Medicine, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt;

    • e. Medical Microbiology and Immunology Department, Faculty of Medicine, Suez Canal University, Ismailia 41111, Egypt;

    • f. Department of Immunology, Faculty of Medicine, New Kaser Al-Aini Teaching Hospital, Cairo University, 11435, Egypt;

    • g. Anhui Provincial Key Laboratory of Animal Nutritional Regulation and Health, College of Animal Science, Anhui Science and Technology University, Fengyang 233100, China;

    • h. Family Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia 41111, Egypt;

    • i. Hubei Hongshan Laboratory, Wuhan 430070, China

    • Corresponding author: Wentao Li, wentao@mail.hzau.edu.cn
    • Received Date: 05 September 2024
      Accepted Date: 10 December 2024
      Available online: 11 December 2024
    • Rotavirus infections cause severe gastroenteritis and dehydration in young children and animals worldwide, leading to high rates of morbidity and mortality, predominantly in low- and middle-income countries. In the past decade, substantial progress has been made in the development and implementation of rotavirus vaccines, which have been essential in alleviating the global burden of this disease, not only in human being but also in livestock species like calves and piglets, where these infections can cause significant economic losses. By synthesizing the latest research and real-world evidence, this review article is designated to provide deep insights into the current state of rotavirus vaccine technology and its global implementation as well as the application of rotavirus vaccines in veterinary settings and their importance in controlling zoonotic transmission and maintaining food security.
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      Insights into recent advancements in human and animal rotavirus vaccines: Exploring new frontiers

        Corresponding author: Wentao Li, wentao@mail.hzau.edu.cn
      • a. National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China;
      • b. The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China;
      • c. Desert Research Center, Cairo 11435, Egypt;
      • d. Department of Veterinary Medicine, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt;
      • e. Medical Microbiology and Immunology Department, Faculty of Medicine, Suez Canal University, Ismailia 41111, Egypt;
      • f. Department of Immunology, Faculty of Medicine, New Kaser Al-Aini Teaching Hospital, Cairo University, 11435, Egypt;
      • g. Anhui Provincial Key Laboratory of Animal Nutritional Regulation and Health, College of Animal Science, Anhui Science and Technology University, Fengyang 233100, China;
      • h. Family Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia 41111, Egypt;
      • i. Hubei Hongshan Laboratory, Wuhan 430070, China
      • Received Date: 05 September 2024
      • Accepted Date: 10 December 2024

      Abstract: Rotavirus infections cause severe gastroenteritis and dehydration in young children and animals worldwide, leading to high rates of morbidity and mortality, predominantly in low- and middle-income countries. In the past decade, substantial progress has been made in the development and implementation of rotavirus vaccines, which have been essential in alleviating the global burden of this disease, not only in human being but also in livestock species like calves and piglets, where these infections can cause significant economic losses. By synthesizing the latest research and real-world evidence, this review article is designated to provide deep insights into the current state of rotavirus vaccine technology and its global implementation as well as the application of rotavirus vaccines in veterinary settings and their importance in controlling zoonotic transmission and maintaining food security.

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