ESTABLISHMENT OF EXPERIMENTAL PERSISTENT INFECTION OF MOUSE CYTOMEGALOVIRUS MODEL

Smith strain of murine cytomegalovirus (MCMV) was used for intraperitoneal infection of C57BL/6 inbred mice. in all three groups of high(10~(5.33)TCID_(50)), medium (2×10~(4.33)TCID_(50))and low (2×10~(3.33)TCID_(50)) dosage infected mice, MCMV infection was successfully established During 5-14 days after infection, in all dosage groups MCMV could be isolated from the spleens Starting from the 14th day after infection, salivary glands from all mice of the high and medium dosage groups were MCMV positive, wh...