Citation: QIU Su-Ying, CAO Zong-Li, DONG Jie-De, CHEN Chen-Hua, ZENG Li, SONG Yuan-Di, XU Xiu-Ping. Study of Biological Properties of Cell Lines Transformed by Herpes Simplex Virus .VIROLOGICA SINICA, 1988, 3(1) : 27.

Study of Biological Properties of Cell Lines Transformed by Herpes Simplex Virus

  • Available online: 05 March 1988
  • The biological properties of three cell lines transformed by HSV-2 were investigated. The results indicate that the transformed cell lines possess the following characteristies:(1) chromosomal abnormalities; (2) reduce of requirement for serum factor; (3) rapid growth; (4) colony formation in soft agar; (5) increase of agglutination by Con Aand(6) induction of malignant tumor in nude mice These strongly suggest that the transformed cells are neoplastic.

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    Study of Biological Properties of Cell Lines Transformed by Herpes Simplex Virus

    • 1. Department of Microbiology
    • 2. Shandong Medical University

    Abstract: The biological properties of three cell lines transformed by HSV-2 were investigated. The results indicate that the transformed cell lines possess the following characteristies:(1) chromosomal abnormalities; (2) reduce of requirement for serum factor; (3) rapid growth; (4) colony formation in soft agar; (5) increase of agglutination by Con Aand(6) induction of malignant tumor in nude mice These strongly suggest that the transformed cells are neoplastic.

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