Studies on Replication of Epidemic Hemorrhagic Fever Virus in Cultured Macrophages Derived from Rodents and Human Blood
Abstract: It was found that the epidemic hemorrhagic fever(EHF) viruses could be replicated well in cultured peritoneal macrophages derived from Mongolian gerbiles, Syrian golden hamster and Balb/c mice as well as in cultured human peripheral blood leukocyte. The sensitivity of maerophages from Mongolian gerbiles and Syrian golden hamster were higher than Vero-E_6-cells, however, the macrophage from Balb/c mouse was less sensitive than the other three. No obvious difference was observed for the replicating ability in...