Study on the Hamster Infected with Epidemic Hemorrhagic Fever Virus
Abstract: It was shown in our study the hamster is susceptible to Epidemic Hemor- rhagic Fever Virus(EHFV) including the wild-mouse type(strains Z_3, Z_4, Z_5, Z_(10), 76—118) and the house-rat type(strains Z_(26), R_(22), SR-11,Z_(30),Z_(34)). The hamster was successfully infected intramuscularly, intraperitoneally, subcutaneously and intrapulmonaryly or intracerebrally (suckling hamster) but not orally. EHFV antigen appeared in lung 5 days after inoculation of EHFV strain Z_5 and persisted for at least 50 days.EHFV...