Citation: Leonard J.Rosenthal, Stephen M.Peters, Abdur Razzaque. Analysis of AIDS KS Biopsy and Peripheral Blood Lymphocyte Specimens for Human Cytomegalovirus Transforming DNA Sequences .VIROLOGICA SINICA, 1988, 3(4) : 317.

Analysis of AIDS KS Biopsy and Peripheral Blood Lymphocyte Specimens for Human Cytomegalovirus Transforming DNA Sequences

  • Available online: 05 December 1988
  • Investigation into the role of human eytomegalovirus (HCMV) in the development of AIDS/KS was carried out by nucleic acid hybridization analyses of both human KS biopsy and peripheral blood lymphocyte (PBL) specimens for the presence of HCMV transforming mtrⅡ and mtrⅢ DNA sequences. In one set of experiments, Southern blot analysis revealed the presence of mtrⅡ sequences in only 2 out of 6 KS biopsies, while mtrⅢ sequences were not detected in any of the biopsies. The general absence of both mtrⅡ and Ⅲ tran...

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    Analysis of AIDS KS Biopsy and Peripheral Blood Lymphocyte Specimens for Human Cytomegalovirus Transforming DNA Sequences

    • 1. Department of Microbiology and Vincent T. Lombardi Cancer Center
    • 2. Department of Pediatrics and Immunology Center Georgetown University Medical Center Washington D. C. 20007 U.S.A

    Abstract: Investigation into the role of human eytomegalovirus (HCMV) in the development of AIDS/KS was carried out by nucleic acid hybridization analyses of both human KS biopsy and peripheral blood lymphocyte (PBL) specimens for the presence of HCMV transforming mtrⅡ and mtrⅢ DNA sequences. In one set of experiments, Southern blot analysis revealed the presence of mtrⅡ sequences in only 2 out of 6 KS biopsies, while mtrⅢ sequences were not detected in any of the biopsies. The general absence of both mtrⅡ and Ⅲ tran...

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