Citation: LIU Hong, YANG Xue-Lou. Production and Some Properties of Porcine Spleen Interferon .VIROLOGICA SINICA, 1988, 3(4) : 389.

Production and Some Properties of Porcine Spleen Interferon

  • Available online: 05 December 1988
  • Porcine spleen cells induced with Newcastle disease virus F strain could produce an antiviral substance. The substance was sensitive to trypsin and did not penetrate the dialyser. These indicated that it was characteristic of an Interferon. The antiviral activity of crude porcine spleen cell interferon(PSIFN)was 1.3×10~5u/ml on porket kidney cells. PSIFN production was significantly enhanced by pretreating cells with porcine IFN. The crude PSIFN was less stable to low pH treatment, to 56℃ and to 0.1% SDS. I...

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    Production and Some Properties of Porcine Spleen Interferon

    • 1. Wuhan Institute of Virology
    • 2. Academia Sinica

    Abstract: Porcine spleen cells induced with Newcastle disease virus F strain could produce an antiviral substance. The substance was sensitive to trypsin and did not penetrate the dialyser. These indicated that it was characteristic of an Interferon. The antiviral activity of crude porcine spleen cell interferon(PSIFN)was 1.3×10~5u/ml on porket kidney cells. PSIFN production was significantly enhanced by pretreating cells with porcine IFN. The crude PSIFN was less stable to low pH treatment, to 56℃ and to 0.1% SDS. I...

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