Detection of Human Papillomavirus and Herpes Simplex Virus Type-2 DNA Sequences in Cervical Lesions
Abstract: 79 cervical lesions(50 cervical cancer and 29 cervical erosion) were studied by dot hybridization using five DNA probes: HPV 16, 18, 11 and HSV-2N/BglⅡ, HSV-2 L/HindⅢ. Among them, the positive percentage of HPV 16, 18 and 11 in cervical carcinoma was 44%, 12% and 4%, respectively; but 14%, 7%, and 14% in cervical erosion, respectively; and 3 samples showed weakly cross-hybridization between HPV 16 and HPV 18. of all cervical carcinoma studied, only 2 hybridize, weakly with HSV-2 N/BglⅡ and HSV-2 L/HindⅢ DNA...