Citation: MENG Xiang-Jin, SUN Yu, LIU Zhi-Hui, CHEN Min-Hui, LI Xin-Zhi, ZHANG Wei-Xin, LI Hun, HAN Ri-Cai, CI Jing-Yi, ZHANG Wei, CENG Wei-Kun, HU Lun-Ying, NONG Shu-Gui. Detection of Human Papillomavirus and Herpes Simplex Virus Type-2 DNA Sequences in Cervical Lesions .VIROLOGICA SINICA, 1989, 4(1) : 22.

Detection of Human Papillomavirus and Herpes Simplex Virus Type-2 DNA Sequences in Cervical Lesions

  • Available online: 05 March 1989
  • 79 cervical lesions(50 cervical cancer and 29 cervical erosion) were studied by dot hybridization using five DNA probes: HPV 16, 18, 11 and HSV-2N/BglⅡ, HSV-2 L/HindⅢ. Among them, the positive percentage of HPV 16, 18 and 11 in cervical carcinoma was 44%, 12% and 4%, respectively; but 14%, 7%, and 14% in cervical erosion, respectively; and 3 samples showed weakly cross-hybridization between HPV 16 and HPV 18. of all cervical carcinoma studied, only 2 hybridize, weakly with HSV-2 N/BglⅡ and HSV-2 L/HindⅢ DNA...

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    Detection of Human Papillomavirus and Herpes Simplex Virus Type-2 DNA Sequences in Cervical Lesions

    • 1. Institute of Virology
    • 2. Hubei Medical College
    • 3. WuhanInstitute of Basic Medical Science
    • 4. Chinese Academy of Medical Science

    Abstract: 79 cervical lesions(50 cervical cancer and 29 cervical erosion) were studied by dot hybridization using five DNA probes: HPV 16, 18, 11 and HSV-2N/BglⅡ, HSV-2 L/HindⅢ. Among them, the positive percentage of HPV 16, 18 and 11 in cervical carcinoma was 44%, 12% and 4%, respectively; but 14%, 7%, and 14% in cervical erosion, respectively; and 3 samples showed weakly cross-hybridization between HPV 16 and HPV 18. of all cervical carcinoma studied, only 2 hybridize, weakly with HSV-2 N/BglⅡ and HSV-2 L/HindⅢ DNA...

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