Citation: TANG En-Hua, PENG Dun-Yang, WANG Li-Yan, LIU Ming-Ying, WEN Yu-Ling, RUAN Yong-Liang, XIE Tian-Hong, GUO Ren. Analysis of Poliovirus Antigenic Epitopes by Immunofluorescence Activated McAbs .VIROLOGICA SINICA, 1989, 4(2) : 135.

Analysis of Poliovirus Antigenic Epitopes by Immunofluorescence Activated McAbs

  • Available online: 05 June 1989
  • 12 McAbs to several strains of poliovirus Type 2 and 3 were selected by IF and NT, 9 McAbs had both neutralizing and immunofluorescence activity,3 McAbs were uniquely with IF staining activity. All the 12 McAbs with immunofluorescence activity reacted with poliovirus Type 2 and 3(F-McAbs) and were found similar to neutranizing McAbs (N-McAbs) recognizing different spesific antigenic epitopes on infected cells. According to topological relationships of antigenic epitopes, it was possible to characterize the ...

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    Analysis of Poliovirus Antigenic Epitopes by Immunofluorescence Activated McAbs

    • 1. Institute of Medical Biology
    • 2. Chinese Academy of Medical Sciences

    Abstract: 12 McAbs to several strains of poliovirus Type 2 and 3 were selected by IF and NT, 9 McAbs had both neutralizing and immunofluorescence activity,3 McAbs were uniquely with IF staining activity. All the 12 McAbs with immunofluorescence activity reacted with poliovirus Type 2 and 3(F-McAbs) and were found similar to neutranizing McAbs (N-McAbs) recognizing different spesific antigenic epitopes on infected cells. According to topological relationships of antigenic epitopes, it was possible to characterize the ...

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