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Volume 04 Issue 2
April 1989
    Citation: HU Ke-Qin, YU Zhi-Qun, ZHANG Yong-Yuan, LI Fang-He, HAO Lian-Jie. Researches on Pre-S Proteins of Hepatitis B Virus Ⅵ. Binding of Pre-S Proteins with Human Serum Albumin .VIROLOGICA SINICA, 1989, 4(2) : 159.
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    Researches on Pre-S Proteins of Hepatitis B Virus Ⅵ. Binding of Pre-S Proteins with Human Serum Albumin

    • 1.

      Division of Clinical Immunology

    • 2.

      Tongji Hospital

    • Available online: 05 June 1989
    • 40 serum samples were used to study the relation of Pre-S_1 and pre-S_2 proteins to polymerized human serum albumin receptor (PHSAR). Our results suggested that pre-S_2 may be the main binding site for PHSA, but pre-S_1 may also possess the activity to bind PHSA. Pre-S_1, pre-S_2 and PHSAR may be blocked in vitro by pretreatment with PHSA and the negative correlation between the blocking rate and the dilution of PHSA was seen. We also showed that the complexes of HBV envelop protein-human serum albumin may ...
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      Researches on Pre-S Proteins of Hepatitis B Virus Ⅵ. Binding of Pre-S Proteins with Human Serum Albumin

      • 1. Division of Clinical Immunology
      • 2. Tongji Hospital

      Abstract: 40 serum samples were used to study the relation of Pre-S_1 and pre-S_2 proteins to polymerized human serum albumin receptor (PHSAR). Our results suggested that pre-S_2 may be the main binding site for PHSA, but pre-S_1 may also possess the activity to bind PHSA. Pre-S_1, pre-S_2 and PHSAR may be blocked in vitro by pretreatment with PHSA and the negative correlation between the blocking rate and the dilution of PHSA was seen. We also showed that the complexes of HBV envelop protein-human serum albumin may ...

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