Citation: LI Hong-Ling, LI He-Min, YU Yong-Xin, YAN Zi-Lin. Application of Plaque Assay Method for Rabies Virus in the Study of Virus and Vaccine .VIROLOGICA SINICA, 1990, 5(2) : 135.

Application of Plaque Assay Method for Rabies Virus in the Study of Virus and Vaccine

  • Available online: 05 June 1990
  • We explored rabies virus adapted to Vero cells making plaque formation promptly.The plaque could be all exposed and easily seen under microscope on 4th day. It was shown that plaque method was more sensitive than mice(i.c) method on the titer of virus and assay neutralizing antibody.Up to now, the plaque formation has been applied to virus cloning, virus identify, virus titration,evaluation of serum-antibody content by the virus neutralization technique,providing an important assay method for the study and ...

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    Application of Plaque Assay Method for Rabies Virus in the Study of Virus and Vaccine

    • 1. National Institute for the Control of Pharmaceutical and Biological Products. Beijing

    Abstract: We explored rabies virus adapted to Vero cells making plaque formation promptly.The plaque could be all exposed and easily seen under microscope on 4th day. It was shown that plaque method was more sensitive than mice(i.c) method on the titer of virus and assay neutralizing antibody.Up to now, the plaque formation has been applied to virus cloning, virus identify, virus titration,evaluation of serum-antibody content by the virus neutralization technique,providing an important assay method for the study and ...

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